Disease: Tauopathies
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TREM2 Q9NZC2 triggering receptor expressed on myeloid cells 2 3.3E-09 0.519 0.769
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TIA1 P31483 TIA1 cytotoxic granule associated RNA binding protein 0.27 0.595 0.577
TARDBP Q13148 TAR DNA binding protein 0.99 0.493 0.808
SQSTM1 Q13501 sequestosome 1 8.6E-04 0.428 0.885
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
PSEN1 P49768 presenilin 1 Enzyme 0.97 0.469 0.846
PIN1 Q13526 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 0.74 0.488 0.769
PARK7 Q99497 Parkinsonism associated deglycase Enzyme 0.75 0.535 0.808
OGA O60502 O-GlcNAcase 0.97 0.534 0.731
NUP62 P37198 nucleoporin 62 Transporter 0.95 0.470 0.885
NEFL P07196 neurofilament light 0.488 0.769
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
LRRK2 Q5S007 leucine rich repeat kinase 2 Kinase 2.6E-30 0.510 0.808
KHDRBS1 Q07666 KH RNA binding domain containing, signal transduction associated 1 Nucleic acid binding 0.99 0.457 0.846
IGFALS P35858 insulin like growth factor binding protein acid labile subunit Receptor 5.4E-11 0.511 0.846
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
HSPB3 Q12988 heat shock protein family B (small) member 3 6.1E-05 0.448 0.769
HSPB2 Q16082 heat shock protein family B (small) member 2 3.3E-04 0.457 0.769
HSPB1 P04792 heat shock protein family B (small) member 1 2.8E-07 0.436 0.808
HDAC6 Q9UBN7 histone deacetylase 6 Epigenetic regulator 1.00 0.465 0.846
GTF2H1 P32780 general transcription factor IIH subunit 1 Transcription factor 0.99 0.469 0.846